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Innate immune responses in RNA viral infection

Qian Xu, Yuting Tang, Gang Huang

Frontiers of Medicine 2021, Volume 15, Issue 3,   Pages 333-346 doi: 10.1007/s11684-020-0776-7

Abstract: Upon viral invasion, the innate immune system responds rapidly and plays a key role in activating theIn this review, the current understanding of innate immunity contributing to the restriction of RNA viralBesides the main role of immune cells in combating viral infection, the intercellular transfer of pathogenThis knowledge provides an enhanced understanding of the innate immune response to RNA viral infectionsin general and aids in the preparation for the existing and next emerging viral infections.

Keywords： innate immune     viral infection     intercellular signaling     metabolic changes     epigenetic changes    

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Evaluating and structuring indicators for wetland assessment

Xuehua LIU, Yan SUN,

Frontiers of Environmental Science & Engineering 2010, Volume 4, Issue 2,   Pages 221-227 doi: 10.1007/s11783-010-0029-0

Abstract: However, various indicators have been used in wetland assessment for different purposes and backgroundsAfter an extensive review of wetland assessment literatures, the reported indicators were evaluated usingThe results of these two methods were compared to study the commonalities and specialties of the indicatorsThey also showed that some indicators were widely used, including biodiversity, weather and climate,On the other hand, other sustainable indicators were easily ignored, such as environmental carrying capacity

Keywords： wetland assessment     indicators     Analytical Hierarchy Process (AHP)     comparison    

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Analysis of antibiotic usage for viral community-acquired pneumonia in adults

Rongmeng Jiang, Bing Han, Chang Dou, Fei Zhou, Bin Cao, Xingwang Li

Frontiers of Medicine 2021, Volume 15, Issue 1,   Pages 139-143 doi: 10.1007/s11684-019-0736-2

Abstract: The rationale for the antibiotic treatment of viral community-acquired pneumonia (CAP) in adults wasClinical data from 166 patients diagnosed with viral pneumonia across 14 hospitals in Beijing from NovemberA total of 163 (98.3%) patients with viral pneumonia were treated with antibiotics.A total of 39 of the 163 (23.9%) patients did not meet the guidelines for drug selection for viral CAPThe unreasonable use of antibacterial drugs for the treatment of viral CAP in adults is a serious concern

Keywords： adult     antibiotic     viral pneumonia    

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Novel soil quality indicators for the evaluation of agricultural management practices: a biological perspective

Giulia BONGIORNO

Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 3,   Pages 257-274 doi: 10.15302/J-FASE-2020323

Abstract: biology and in methods to characterize soil organic carbon can potentially deliver novel soil quality indicatorsregarding the suitability of a range of soil biological and biochemical properties as novel soil quality indicatorsPrior studies tested the sensitivity of each of the novel indicators to tillage and organic matter additionlong-term field experiments (LTEs) and assessed their relationships with pre-existing soil quality indicatorsThe novel indicators proposed here have great potential to improve existing soil quality assessment schemes

Keywords： labile carbon     long-term field experiments     organic matter addition     soil biological indicators     tillage    

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Correlation between viral load and liver cirrhosis in chronic hepatitis B patients

Lili LIU MM , Jiyao WANG MD , Weimin SHE MM ,

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 271-276 doi: 10.1007/s11684-009-0054-1

Abstract: The aim of this paper is to investigate the relationship between hepatitis B virus (HBV) DNA levels during the course and the progression to cirrhosis with chronic hepatitis B. A total of 239 chronic hepatitis B patients confirmed by liver biopsy between 2001 and 2007 were followed up for a median of 28 months. Compared with the patients without cirrhosis, the patients progressed to cirrhosis were older and with higher HBV-DNA levels at end point. However, there was no significant difference in cirrhosis progression between different HBV-DNA groups at baseline ( = 0.531). Kaplan-Meier analysis showed higher HBV-DNA level at endpoint had increasing risk of cirrhosis ( = 0.019). The results of Cox model indicated that HBV-DNA levels at endpoint, stage of fibrosis, negative hepatitis B e antigen, and γ-glutamyl transpeptidase at baseline were independent risk factors of cirrhosis. The relative risk ratios were 1.898, 1.918, 8.976, and 1.006, respectively. Progression to cirrhosis in chronic hepatitis B patients is correlated with HBV-DNA levels during follow-up.

Keywords： hepatitis B     chronic     viral load     liver cirrhosis    

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A model for the evaluation of environmental impact indicators for a sustainable maritime transportation

Lizzette Pérez LESPIER, Suzanna LONG, Tom SHOBERG, Steven CORNS

Frontiers of Engineering Management 2019, Volume 6, Issue 3,   Pages 368-383 doi: 10.1007/s42524-019-0004-9

Abstract: In-depth studies of maritime transportation systems (MTS) can be used to identify key environmental impact indicatorsdecision making in complex environments; this tool will quantify and rank preferred environmental impact indicators

Keywords： Environmental sustainability     maritime transportation system     environmental impact indicators     fuzzy analytic    

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A review of soil nematodes as biological indicators for the assessment of soil health

Qiaofang LU, Tongtong LIU, Nanqi WANG, Zhechao DOU, Kunguang WANG, Yuanmei ZUO

Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 3,   Pages 275-281 doi: 10.15302/J-FASE-2020327

Abstract: Physical, chemical and biological indicators are used to evaluate soil health; the biological indicatorsSoil nematode communities are useful biological indicators of soil health, with community characteristicsBoth free-living and plant-parasitic nematodes are effective ecological indicators, contributing to nutrientlaboratory and because of these advantages soil nematodes are increasingly being used as biological indicators

Keywords： biological indicators     community characteristics     soil health     soil nematodes    

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Evaluation of ICUs and weight of quality control indicators: an exploratory study based on Chinese ICU

Frontiers of Medicine 2023, Volume 17, Issue 4,   Pages 675-684 doi: 10.1007/s11684-022-0970-x

Abstract: We found that 15 initially established quality control indicators were good predictors of patient prognosisWhen exploratory factor analysis was applied, the 15 indicators were divided into 6 core elements thatBased on the different weights of the core elements associated with the 15 indicators, we developed an

Keywords： critical care medicine     quality control     evaluation     exploratory factor analysis (EFA) model    

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Potential indicators predict progress after surgical resection of gastrointestinal stromal tumors

Qinggang Hu, Shanglong Liu, Jianwei Jiang, Chen Zhang, Xiaowei Liu, Qichang Zheng

Frontiers of Medicine 2012, Volume 6, Issue 3,   Pages 317-321 doi: 10.1007/s11684-012-0203-9

Abstract:

In order to find out the potential indicators predicting prognosis of malignant gastrointestinal stromal

Keywords： gastrointestinal stromal tumors     surgery     survival    

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Transgenic technologies in cassava for nutritional improvement and viral disease resistance: a key strategy

Maliwan NACONSIE,Peng ZHANG

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 4,   Pages 285-294 doi: 10.15302/J-FASE-2016119

Abstract: Also, two viral diseases, cassava mosaic disease (CMD) and cassava brown streak disease (CBSD), causeGenetic engineering provides promising approaches to improve nutritional value and increase resistance to viralprotein content by overexpression of nutritious storage proteins and improving cassava resistance to viral

Keywords： Manihot esculenta     protein enhancement     RNA interference     transgenesis     virus resistance    

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Development of small-molecule viral inhibitors targeting various stages of the life cycle of emerging

Xiaohuan Wang, Peng Zou, Fan Wu, Lu Lu, Shibo Jiang

Frontiers of Medicine 2017, Volume 11, Issue 4,   Pages 449-461 doi: 10.1007/s11684-017-0589-5

Abstract: In this review, we summarize and discuss the latest progress in the development of small-molecule viralThese viruses can interfere with the specific steps of viral life cycle by blocking the binding betweenvirus and host cells, disrupting viral endocytosis, disturbing membrane fusion, and interrupting viralWe also discuss some general strategies for developing small-molecule viral inhibitors.

Keywords： emerging and re-emerging viruses     small-molecule inhibitor     coronavirus     Ebola virus     Zika virus     life cycle    

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A brief review of microRNA and its role in PRRSV infection and replication

Xuekun GUO,Wenhai FENG

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 2,   Pages 114-120 doi: 10.15302/J-FASE-2014022

Abstract: shown to be capable of modulating PRRSV infection and replication by multiple ways such as targeting viralgenomic RNA, targeting viral receptor and inducing antiviral response.

Keywords： porcine reproductive and respiratory syndrome virus (PRRSV)     microRNA     antiviral     viral tropism    

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Photochemical indicators of ozone sensitivity: application in the Pearl River Delta, China

Lyumeng Ye,Xuemei Wang,Shaofeng Fan,Weihua Chen,Ming Chang,Shengzhen Zhou,Zhiyong Wu,Qi Fan

Frontiers of Environmental Science & Engineering 2016, Volume 10, Issue 6, doi: 10.1007/s11783-016-0887-1

Abstract: The effectiveness of six popular chemical indicators for discriminating O sensitivity regimes is evaluatedThe indicators H O /HNO and H O /NO performed best and maintained relatively stable threshold levelsAll indicators produced good representations of the elevated ozone hours in the episode on 6 NovemberThreshold intervals for the indicators H O /HNO , O /NO , O /NO , O /HNO , and H O /NO were able toSince the species used for indicators have seasonal variation, the utility of those indicators for other

Keywords： Ozone     Pearl River Delta (PRD)     Sensitivity regime     Photochemical indicator     Threshold levels    

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Preliminary research on quantitative indicators for ecological civilization city construction of Taihu

Zhu Zengyin,Li Bing,Gao Ming,Tian Aijun

Strategic Study of CAE 2010, Volume 12, Issue 6,   Pages 131-136

Abstract: cities in Taihu Lake Basin for example, a framework constitutes of five-system and three-layer with 41 indicators

Keywords： ecological civilization     indicators     quantitative     Taihu Lake Basin    

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Systematic exploration of signal-based indicators for failure diagnosis in the context of cyber-physical None

Santiago RUIZ-ARENAS, Zoltán RUSÁK, Imre HORVÁTH, Ricardo MEJÍ-GUTIERREZ

Frontiers of Information Technology & Electronic Engineering 2019, Volume 20, Issue 2,   Pages 152-175 doi: 10.1631/FITEE.1700277

Abstract: There is a practical approach for identifying and forecasting failures based on the indicators obtained

Keywords： Failure indicators     Failure classification     Failure detection and diagnosis     Complex systems    

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Title Author Date Type Operation

Innate immune responses in RNA viral infection

Qian Xu, Yuting Tang, Gang Huang

Journal Article

Evaluating and structuring indicators for wetland assessment

Xuehua LIU, Yan SUN,

Journal Article

Analysis of antibiotic usage for viral community-acquired pneumonia in adults

Rongmeng Jiang, Bing Han, Chang Dou, Fei Zhou, Bin Cao, Xingwang Li

Journal Article

Novel soil quality indicators for the evaluation of agricultural management practices: a biological perspective

Giulia BONGIORNO

Journal Article

Correlation between viral load and liver cirrhosis in chronic hepatitis B patients

Lili LIU MM , Jiyao WANG MD , Weimin SHE MM ,

Journal Article

A model for the evaluation of environmental impact indicators for a sustainable maritime transportation

Lizzette Pérez LESPIER, Suzanna LONG, Tom SHOBERG, Steven CORNS

Journal Article

A review of soil nematodes as biological indicators for the assessment of soil health

Qiaofang LU, Tongtong LIU, Nanqi WANG, Zhechao DOU, Kunguang WANG, Yuanmei ZUO

Journal Article

Evaluation of ICUs and weight of quality control indicators: an exploratory study based on Chinese ICU

Journal Article

Potential indicators predict progress after surgical resection of gastrointestinal stromal tumors

Qinggang Hu, Shanglong Liu, Jianwei Jiang, Chen Zhang, Xiaowei Liu, Qichang Zheng

Journal Article

Transgenic technologies in cassava for nutritional improvement and viral disease resistance: a key strategy

Maliwan NACONSIE,Peng ZHANG

Journal Article

Development of small-molecule viral inhibitors targeting various stages of the life cycle of emerging

Xiaohuan Wang, Peng Zou, Fan Wu, Lu Lu, Shibo Jiang

Journal Article

A brief review of microRNA and its role in PRRSV infection and replication

Xuekun GUO,Wenhai FENG

Journal Article

Photochemical indicators of ozone sensitivity: application in the Pearl River Delta, China

Lyumeng Ye,Xuemei Wang,Shaofeng Fan,Weihua Chen,Ming Chang,Shengzhen Zhou,Zhiyong Wu,Qi Fan

Journal Article

Preliminary research on quantitative indicators for ecological civilization city construction of Taihu

Zhu Zengyin,Li Bing,Gao Ming,Tian Aijun

Journal Article

Systematic exploration of signal-based indicators for failure diagnosis in the context of cyber-physical

Santiago RUIZ-ARENAS, Zoltán RUSÁK, Imre HORVÁTH, Ricardo MEJÍ-GUTIERREZ

Journal Article